polydatin相关论文
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Polydatin (PD) is a kind of natural extract of stilbenoid from plants with a variety of pharmacological activities[1].Ho......
Polydatin Protects Bone Marrow Stem Cells against Oxidative Injury: Involvement of Nrf 2/ARE Pathway
Polydatin, a glucoside of resveratrol, has been reported to possess potent antioxidative effects....
Objective: This aim of this research was to observe the protective effects of polydatin against hypoxia-induced apoptosi......
Polydatin promotes Nrf2-ARE anti-oxidative pathway through activating Sirt1 to resist AGEs-induced u
Sirt1 and nuclear factor-E2 related factor 2 (Nrf2)-anti-oxidant response element (ARE) anti-oxidative pathway play impo......
In this paper,in order to further reduce the cost of β-Glucosidase on the degradation of Polygdatin,β-Glucosidase was ......
Matrix effect on the release of resveratrol and polydatin from the fufang huzhang(FFHZ)semi-solid ca
Purpose : Choosing the suit matrix for FFHZ semisolid controlled release capsule.The effect of different matrix on the r......
Polydatin protects cardiac function against burn injury by inhibiting sarcoplasmic reticulum Ca2+ le
Background: Our recent studiesdemonstrate that burn trauma induces leaky sarcoplasmic reticulum (SR) in heart due to......
Polydatin prevents the induction of secondary brain injury after traumatic brain injury by protectin
Polydatin is thought to protect mitochondria in different cell types in various diseases. Mitochondrial dysfunction is a......
[Objectives]To establish a UPLC-UV method for the determination of polydatin in the serum of Wistar rats.[Methods]Acquit......
目的建立HPLC法同时测定肝力保胶囊中绿原酸和虎杖苷的含量。方法色谱柱为Agilent ZORBAX SBC18,流动相为0.1%甲酸-乙腈梯度洗脱,......
Polydatin attenuates renal fibrosis in diabetic mice through regulating the Cx32-Nox4 signaling path
We previously found that polydatin could attenuate renal oxidative stress in diabetic mice and improve renal fibrosis.Re......
目的研究白藜芦醇苷(PD)对内毒素休克大鼠肺组织中Clara细胞分泌蛋白(CCSP)基因和蛋白表达的影响及量效关系。方法50只SD大鼠随机......
目的 采用微透析技术研究虎杖苷的体外血浆蛋白结合率,并与超滤法比较.方法 微透析探针依次浸入含虎杖苷20,60,200 μg·mL-1的大......
目的 研究虎杖苷对卵巢摘除骨质疏松大鼠β-Catenin及GSK-3β蛋白表达的影响,探索其对卵巢摘除骨质疏松大鼠的保护作用及可能的作......
,Polydatin ameliorates Staphylococcus aureus-induced mastitis in mice via inhibiting TLR2-mediated a
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目的:优选赤丹肝纤颗粒的醇提最佳工艺。方法:以虎杖苷含量为考察指标,先优选出最佳乙醇浓度,再采用L9(34)正交试验法,考察提取次......
Objective: To study the effect of polydatin on p hospholipase A_2 in lung tissues in rats with endotoxic shock. Methods:......
目的 探讨白藜芦醇甙(PD)对缺氧缺血性脑损伤(HIBD)新生大鼠空间学习记忆的影响及海马CA1区突触素表达的变化.方法 7日龄SD大鼠37......
[目的]研究虎杖苷治疗对非酒精性脂肪性肝病(NAFLD)胰岛素抵抗(IR)及氧化应激的影响.[方法]健康雄性SD大鼠47只,随机分为5组:正常......
目的:研究并完善藜芦的质量控制。方法:采用薄层色谱法鉴别藜芦;采用HPLC法同时测定藜芦中虎杖苷和白藜芦醇的含量,采用Thermo C18......
目的探究虎杖苷对大鼠肝脏缺血再灌注损伤(HIR)的保护作用及其与核因子E2相关因子2(Nrf2)/血红素氧合酶1(HO⁃1)信号通路的作用关......
目的:建立虎黄烧伤搽剂中虎杖苷的含量测定方法。方法:高效液相色谱法(HPLC)条件:以Diamonsil C18(5μm,250 mm×4.6 mm)色谱柱分离,......
采用分光光度法、TLC、HPLC、MS等,对白藜芦醇苷水解产物进行了鉴定;通过单因子和多因子的正交试验,确定了白藜芦醇苷水解产生白藜芦......
通过构建虎杖浮床对其净水能力进行研究,高效液相测定土生、水生虎杖根、叶中虎杖苷含量。结果显示:水生虎杖生长状况良好,粗壮浮......
目的:建立护肝宁丸中虎杖苷、槲皮素和丹参酮ⅡA的测定方法。方法:采用Phenomenex Luna C18色谱柱(4.6mm×250mm,5μm);流动相为甲......
目的 探讨白藜芦醇甙对缺氧缺血性脑损伤(HIBD)新生大鼠大脑海马c Jun表达的影响.方法 选择新生7日龄SD大鼠52只,随机分为假手术对照......
目的:建立补正片中虎杖苷、补骨脂素及异补骨脂素的液相色谱测定方法。方法采用高效液相色谱法。色谱柱为Venusil XBP C18(250mm......
目的:研究虎杖苷(PD)对严重烧伤小鼠早期肠损伤及沉默信息调节因子1(SIRT1)/核转录因子-κB(NF-κB)通路的影响。方法:建立严重烧......
采用量子化学的密度泛函理论,在B3LYP/6-31G(D)水平上对白藜芦醇甙(白藜芦醇与葡萄糖形成的糖甙)进行全优化Opt和频率Freq计算,结合有机结......
目的:采用高效液相色谱法(HPLC)测定虎梅含片中白藜芦醇苷的含量。以控制该制剂的质量。方法:采用Shim-pack CLC—ODS柱,以乙腈-水(18:82)......
目的 :探讨中药虎杖提取物 -虎杖甙扩张休克动物细动脉、改善微循环灌流的作用机制。方法 :应用膜片钳技术的细胞贴附式观察虎杖甙......
目的:建立前列回春丸中虎杖苷含量测定的方法。方法:Hypersil ODS2 Cl8柱(4.6mm×250mm,5μm);检测波长:306nm;流动相:乙腈-水(19∶81......
目的观察虎杖苷(PD)对肺血管内皮细胞(PECs)正常及缺氧培养条件下合成一氧化氮(NO)的影响从而探讨PD抗休克的可能作用机制。方法将Griess......
目的研究白藜芦醇甙(PD)对休克大鼠肺损伤的干预机制.方法将休克性肺损伤大鼠随机分为4组:单纯手术组、内毒素休克组、PD预防组和PD治......
目的建立测定清肝利胆排石丸中虎杖苷含量的高效液相色谱(HPLC)法。方法色谱柱为Kromasil C18柱(250 mm×4.6 mm,5μm),流动相为乙......
目的建立测定抑毒调肝合剂中虎杖苷含量的高效液相色谱(HPLC)法。方法色谱柱为Hypersil C18柱(250 mm×4.6 mm,5μm),流动相为乙腈......
目的建立测定降脂颗粒中的虎杖苷、二苯乙烯苷、橙皮苷含量的高效液相色谱法。方法色谱柱为Kromasil C18柱(250 mm×4.6 mm,5μm),......
目的建立测定通降颗.粒中虎杖苷含量的高效液相色谱(EffiLC)法。方法色谱柱为COSMOSIL Cholester柱(250mmX4.6mm,5um),流动相为乙腈-......
目的:探讨虎杖甙(PD)抗肺缺血/再灌注损伤作用及其机制。方法:采用在体兔单肺原位缺血/再灌注损伤模型。健康日本大耳白兔40只随机均分......
目的:研究白藜芦醇甙对慢性酒精中毒大鼠学习记忆及前额叶皮质区细胞周期依赖性蛋白激酶5(cdk5)表达的影响。方法:建立大鼠慢性酒精中......
目的探讨早期应用虎杖甙(polydatin,PD)在治疗重症急性胰腺炎(severe acute pancreatitis,SAP)大鼠中的作用及其可能的机制。方法将SD......
应用产β-葡萄糖苷酶的黑曲霉固态发酵酶解虎杖中的虎杖苷,以提高虎杖中白藜芦醇的含量。采用均匀实验设计和响应面分析方法对影响......
用放射免疫分析法测定培养液中6-Keto-PGF<sub>1α</sub>浓度的方法研究了虎杖晶Ⅳ(Polydatin,PD)对原代培养的人脐静脉内皮细胞释放......
用邻苯三酚(0.6mmol/L)对肝细胞的氧化损伤模型观察了白藜芦 醇甙对肝细胞的作用。结果表明,白藜芦醇甙0.05、0.1、0.5、1.2及4mmol/L 作......
目的:研究虎杖苷(polydatin)对肝脏药物代谢酶的影响。方法:小鼠灌服虎杖苷240、120和60mg/ks,给药7天,测定肝微粒体细胞色素P450、b5含量......
NTRODUCTIONPolygonumcuspidatumSieb.etZucc.(Polygonaceae)isatraditionalChineseherbaldrug,withbitertasteandcoldnature.Itmainly.........
NTRODUCTIONPolygonumcuspidatumSieb.etZucc.(Polygonaceae)isatraditionalChineseherbaldrug,withbitertasteandcoldnature.Itmainly.........
目的建立RP-HPLC测定大鼠血浆及组织样本中虎杖苷的方法,研究虎杖苷在大鼠体内的药动学行为和组织分布特点。方法采用Diamonsil C18......